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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HIPK1 All Species: 23.94
Human Site: T551 Identified Species: 75.24
UniProt: Q86Z02 Number Species: 7
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86Z02 NP_689909.2 1210 130843 T551 R R V H M Y D T V S Q I K S P
Chimpanzee Pan troglodytes XP_001151260 1210 130923 T551 R R V H M Y D T V S Q I K S P
Rhesus Macaque Macaca mulatta XP_001111238 1210 130747 T551 R R V H M Y D T V S Q I K S P
Dog Lupus familis XP_533012 1209 130666 T551 R R V H M Y D T V S Q I K S P
Cat Felis silvestris
Mouse Mus musculus O88904 1210 130704 T551 R R V H M Y D T V S Q I K S P
Rat Rattus norvegicus A4L9P5 1211 130782 T551 R R V H M Y D T V S Q I K S P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q2TAE3 750 84138 K106 I N E V Y Y A K K K R R H Q Q
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P49657 908 95884 S263 N T N F R G V S L N L T R K F
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 99.4 98.3 N.A. 97.6 97.2 N.A. N.A. N.A. 22.8 N.A. N.A. 22.7 N.A. N.A. N.A.
Protein Similarity: 100 99.9 99.5 99 N.A. 98.8 98.4 N.A. N.A. N.A. 35.5 N.A. N.A. 36.9 N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. N.A. 6.6 N.A. N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. N.A. 13.3 N.A. N.A. 26.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 13 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 75 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 13 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 13 0 0 0 0 0 0 0 0 0 0 13 % F
% Gly: 0 0 0 0 0 13 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 75 0 0 0 0 0 0 0 0 13 0 0 % H
% Ile: 13 0 0 0 0 0 0 0 0 0 0 75 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 13 13 13 0 0 75 13 0 % K
% Leu: 0 0 0 0 0 0 0 0 13 0 13 0 0 0 0 % L
% Met: 0 0 0 0 75 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 13 13 13 0 0 0 0 0 0 13 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 75 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 75 0 0 13 13 % Q
% Arg: 75 75 0 0 13 0 0 0 0 0 13 13 13 0 0 % R
% Ser: 0 0 0 0 0 0 0 13 0 75 0 0 0 75 0 % S
% Thr: 0 13 0 0 0 0 0 75 0 0 0 13 0 0 0 % T
% Val: 0 0 75 13 0 0 13 0 75 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 13 88 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _